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Engl J Med

The second trial, IMPACT 2, had a similar design, except that crossover to active therapy for the placebo arm took place at 24 weeks, although patients with active disease could enter an early escape at 16 weeks

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Same number of units, different concentration, completely different dose

For assistance in Tanzania, we also thank Robert Fyumagwa, Annie Francis, Ernest Eblate Mjingo, Maulid Luziga and Grant Hopcraft